Plasmid

Part:BBa_I713001:Design

Designed by: Zhenyu Shi   Group: iGEM07_Tsinghua   (2007-10-25)

A pBBR1MCS plasmid without the mob gene.


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 25
    Illegal EcoRI site found at 772
    Illegal XbaI site found at 4172
    Illegal SpeI site found at 1
    Illegal PstI site found at 19
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 25
    Illegal EcoRI site found at 772
    Illegal NheI site found at 1484
    Illegal NheI site found at 1498
    Illegal SpeI site found at 1
    Illegal PstI site found at 19
    Illegal NotI site found at 4164
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 25
    Illegal EcoRI site found at 772
    Illegal BamHI site found at 7
    Illegal XhoI site found at 58
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 25
    Illegal EcoRI site found at 772
    Illegal XbaI site found at 4172
    Illegal SpeI site found at 1
    Illegal PstI site found at 19
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 25
    Illegal EcoRI site found at 772
    Illegal XbaI site found at 4172
    Illegal SpeI site found at 1
    Illegal PstI site found at 19
    Illegal NgoMIV site found at 3525
    Illegal AgeI site found at 3685
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 1461


Design Notes

The PCR product is a bit long. So we choose to design long primers for Takara LA Taq.

  • RS 18:18, 4 September 2008 (UTC): The sequence for this part has been reentered to begin with SpeI in keeping with the BioBrick plasmid convention. Feature annotations have been added.

Source

Plasmid: pBBR1MCS Primer:

DMOBF: AATTGCTAGCTGACGTACTCGACCGCCAACACAGC DMOBR: AATAGCTAGCATCCCAAGAGACGGCCCGAGACCTTC

LOCUS pBBR1MCS 4707 bp DNA circular SYN 4-JUN-2007 DEFINITION Cloning vector pBBR1MCS, complete sequence. ACCESSION U02374 SOURCE Cloning vector pBBR1MCS.

ORGANISM  Cloning vector pBBR1MCS
          artificial sequence; vectors.

REFERENCE 1 (bases 1 to 4707)

AUTHORS   Kovach,M.E., Phillips,R.W., Elzer,P.H., Roop,R.M. 2nd and
          Peterson,K.M.
TITLE     pBBR1MCS: a broad-host-range cloning vector
JOURNAL   BioTechniques 16 (5), 800-802 (1994)
MEDLINE   94347360

REFERENCE 2 (bases 1 to 4707)

AUTHORS   Kovach,M.E., Elzer,P.H., Hill,D.S., Robertson,G.T., Farris,M.A.,
          Roop,R.M. II and Peterson,K.M.
TITLE     Four new derivatives of the broad-host-range cloning vector
          pBBR1MCS, carrying different antibiotic-resistance cassettes
JOURNAL   Gene 166 (1), 175-176 (1995)
MEDLINE   96105222

REFERENCE 3 (bases 1 to 4707)

AUTHORS   Kovach,M.E.
TITLE     Direct Submission
JOURNAL   Submitted (05-OCT-1993) Michael E. Kovach, Microbiology &
          Immunology, Louisiana State University Medical Center-Shreveport,
          1501 Kings Highway, Shreveport, LA 71130, USA

BASE COUNT 966 a 1380 c 1329 g 1032 t ORIGIN

      1 ctcgggccgt ctcttgggct tgatcggcct tcttgcgcat ctcacgcgct cctgcggcgg 
     61 cctgtagggc aggctcatac ccctgccgaa ccgcttttgt cagccggtcg gccacggctt 
    121 ccggcgtctc aacgcgcttt gagattccca gcttttcggc caatccctgc ggtgcatagg 
    181 cgcgtggctc gaccgcttgc gggctgatgg tgacgtggcc cactggtggc cgctccaggg 
    241 cctcgtagaa cgcctgaatg cgcgtgtgac gtgccttgct gccctcgatg ccccgttgca 
    301 gccctagatc ggccacagcg gccgcaaacg tggtctggtc gcgggtcatc tgcgctttgt 
    361 tgccgatgaa ctccttggcc gacagcctgc cgtcctgcgt cagcggcacc acgaacgcgg 
    421 tcatgtgcgg gctggtttcg tcacggtgga tgctggccgt cacgatgcga tccgccccgt 
    481 acttgtccgc cagccacttg tgcgccttct cgaagaacgc cgcctgctgt tcttggctgg 
    541 ccgacttcca ccattccggg ctggccgtca tgacgtactc gaccgccaac acagcgtcct 
    601 tgcgccgctt ctctggcagc aactcgcgca gtcggcccat cgcttcatcg gtgctgctgg 
    661 ccgcccagtg ctcgttctct ggcgtcctgc tggcgtcagc gttgggcgtc tcgcgctcgc 
    721 ggtaggcgtg cttgagactg gccgccacgt tgcccatttt cgccagcttc ttgcatcgca 
    781 tgatcgcgta tgccgccatg cctgcccctc ccttttggtg tccaaccggc tcgacggggg 
    841 cagcgcaagg cggtgcctcc ggcgggccac tcaatgcttg agtatactca ctagactttg 
    901 cttcgcaaag tcgtgaccgc ctacggcggc tgcggcgccc tacgggcttg ctctccgggc 
    961 ttcgccctgc gcggtcgctg cgctcccttg ccagcccgtg gatatgtgga cgatggccgc 
   1021 gagcggccac cggctggctc gcttcgctcg gcccgtggac aaccctgctg gacaagctga 
   1081 tggacaggct gcgcctgccc acgagcttga ccacagggat tgcccaccgg ctacccagcc 
   1141 ttcgaccaca tacccaccgg ctccaactgc gcggcctgcg gccttgcccc atcaattttt 
   1201 ttaattttct ctggggaaaa gcctccggcc tgcggcctgc gcgcttcgct tgccggttgg 
   1261 acaccaagtg gaaggcgggt caaggctcgc gcagcgaccg cgcagcggct tggccttgac 
   1321 gcgcctggaa cgacccaagc ctatgcgagt gggggcagtc gaaggcgaag cccgcccgcc 
   1381 tgccccccga gcctcacggc ggcgagtgcg ggggttccaa gggggcagcg ccaccttggg 
   1441 caaggccgaa ggccgcgcag tcgatcaaca agccccggag gggccacttt ttgccggagg 
   1501 gggagccgcg ccgaaggcgt gggggaaccc cgcaggggtg cccttctttg ggcaccaaag 
   1561 aactagatat agggcgaaat gcgaaagact taaaaatcaa caacttaaaa aaggggggta 
   1621 cgcaacagct cattgcggca ccccccgcaa tagctcattg cgtaggttaa agaaaatctg 
   1681 taattgactg ccacttttac gcaacgcata attgttgtcg cgctgccgaa aagttgcagc 
   1741 tgattgcgca tggtgccgca accgtgcggc accctaccgc atggagataa gcatggccac 
   1801 gcagtccaga gaaatcggca ttcaagccaa gaacaagccc ggtcactggg tgcaaacgga 
   1861 acgcaaagcg catgaggcgt gggccgggct tattgcgagg aaacccacgg cggcaatgct 
   1921 gctgcatcac ctcgtggcgc agatgggcca ccagaacgcc gtggtggtca gccagaagac 
   1981 actttccaag ctcatcggac gttctttgcg gacggtccaa tacgcagtca aggacttggt 
   2041 ggccgagcgc tggatctccg tcgtgaagct caacggcccc ggcaccgtgt cggcctacgt 
   2101 ggtcaatgac cgcgtggcgt ggggccagcc ccgcgaccag ttgcgcctgt cggtgttcag 
   2161 tgccgccgtg gtggttgatc acgacgacca ggacgaatcg ctgttggggc atggcgacct 
   2221 gcgccgcatc ccgaccctgt atccgggcga gcagcaacta ccgaccggcc ccggcgagga 
   2281 gccgcccagc cagcccggca ttccgggcat ggaaccagac ctgccagcct tgaccgaaac 
   2341 ggaggaatgg gaacggcgcg ggcagcagcg cctgccgatg cccgatgagc cgtgttttct 
   2401 ggacgatggc gagccgttgg agccgccgac acgggtcacg ctgccgcgcc ggtagcactt 
   2461 gggttgcgca gcaacccgta agtgcgctgt tccagactat cggctgtagc cgcctcgccg 
   2521 ccctatacct tgtctgcctc cccgcgttgc gtcgcggtgc atggagccgg gccacctcga 
   2581 cctgaatgga agccggcggc acctcgctaa cggattcacc gtttttatca ggctctggga 
   2641 ggcagaataa atgatcatat cgtcaattat tacctccacg gggagagcct gagcaaactg 
   2701 gcctcaggca tttgagaagc acacggtcac actgcttccg gtagtcaata aaccggtaaa 
   2761 ccagcaatag acataagcgg ctatttaacg accctgccct gaaccgacga ccgggtcgaa 
   2821 tttgctttcg aatttctgcc attcatccgc ttattatcac ttattcaggc gtagcaccag 
   2881 gcgtttaagg gcaccaataa ctgccttaaa aaaattacgc cccgccctgc cactcatcgc 
   2941 agtcggccta ttggttaaaa aatgagctga tttaacaaaa atttaacgcg aattttaaca 
   3001 aaatattaac gcttacaatt tccattcgcc attcaggctg cgcaactgtt gggaagggcg 
   3061 atcggtgcgg gcctcttcgc tattacgcca gctggcgaaa gggggatgtg ctgcaaggcg 
   3121 attaagttgg gtaacgccag ggttttccca gtcacgacgt tgtaaaacga cggccagtga 
   3181 gcgcgcgtaa tacgactcac tatagggcga attggagctc caccgcggtg gcggccgctc 
   3241 tagaactagt ggatcccccg ggctgcagga attcgatatc aagcttatcg ataccgtcga 
   3301 cctcgagggg gggcccggta cccagctttt gttcccttta gtgagggtta attgcgcgct 
   3361 tggcgtaatc atggtcatag ctgtttcctg tgtgaaattg ttatccgctc acaattccac 
   3421 acaacatacg agccggaagc ataaagtgta aagcctgggg tgcctaatga gtgagctaac 
   3481 tcacattaat tgcgttgcgc tcactgcccg ctttccagtc gggaaacctg tcgtgccagc 
   3541 tgcattaatg aatcggccaa cgcgcgggga gaggcggttt gcgtattggg cgcatgcata 
   3601 aaaactgttg taattcatta agcattctgc cgacatggaa gccatcacaa acggcatgat 
   3661 gaacctgaat cgccagcggc atcagcacct tgtcgccttg cgtataatat ttgcccatgg 
   3721 tgaaaacggg ggcgaagaag ttgtccatat tggccacgtt taaatcaaaa ctggtgaaac 
   3781 tcacccaggg attggctgag acgaaaaaca tattctcaat aaacccttta gggaaatagg 
   3841 ccaggttttc accgtaacac gccacatctt gcgaatatat gtgtagaaac tgccggaaat 
   3901 cgtcgtggta ttcactccag agcgatgaaa acgtttcagt ttgctcatgg aaaacggtgt 
   3961 aacaagggtg aacactatcc catatcacca gctcaccgtc tttcattgcc atacggaatt 
   4021 ccggatgagc attcatcagg cgggcaagaa tgtgaataaa ggccggataa aacttgtgct 
   4081 tatttttctt tacggtcttt aaaaaggccg taatatccag ctgaacggtc tggttatagg 
   4141 tacattgagc aactgactga aatgcctcaa aatgttcttt acgatgccat tgggatatat 
   4201 caacggtggt atatccagtg atttttttct ccattttagc ttccttagct cctgaaaatc 
   4261 tcgataactc aaaaaatacg cccggtagtg atcttatttc attatggtga aagttggaac 
   4321 ctcttacgtg ccgatcaacg tctcattttc gccaaaagtt ggcccagggc ttcccggtat 
   4381 caacagggac accaggattt atttattctg cgaagtgatc ttccgtcaca ggtatttatt 
   4441 cgaagacgaa agggcctcgt gatacgccta tttttatagg ttaatgtcat gataataatg 
   4501 gtttcttaga cgtcaggtgg cacttttcgg ggaaatgtgc gcgcccgcgt tcctgctggc 
   4561 gctgggcctg tttctggcgc tggacttccc gctgttccgt cagcagcttt tcgcccacgg 
   4621 ccttgatgat cgcggcggcc ttggcctgca tatcccgatt caacggcccc agggcgtcca 
   4681 gaacgggctt caggcgctcc cgaaggt 

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References